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Low free testosterone is an independent risk factor for Alzheimer's disease.

Abstract:

The purpose of this study was to assess pituitary gonadotropins and free testosterone levels in a larger cohort of men with Alzheimer's disease (AD, n=112) and age-matched controls (n=98) from the Oxford Project to Investigate Memory and Ageing (OPTIMA). We measured gonadotropins (follicle stimulating hormone, FSH, and luteinizing hormone, LH), sex hormone binding globulin (SHBG, which determines the amount of free testosterone) and total testosterone (TT) using enzyme immunoassays. AD cases ...

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Publication status:
Published

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Publisher copy:
10.1016/j.exger.2004.06.019

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
Journal:
Experimental gerontology
Volume:
39
Issue:
11-12
Pages:
1633-1639
Publication date:
2004-11-05
DOI:
EISSN:
1873-6815
ISSN:
0531-5565
URN:
uuid:1471c278-2911-46f7-8bab-52115895c8ba
Source identifiers:
195485
Local pid:
pubs:195485

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