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Pathological and electrophysiological features of a canine cone-rod dystrophy in the miniature longhaired dachshund.

Abstract:

PURPOSE: To characterize the electrophysiological and histopathological features of a retinal degenerative disease in a colony of miniature longhaired dachshunds known to have a form of progressive retinal atrophy (PRA). METHODS: Serial electroretinograms were recorded from affected homozygous (n = 36) and heterozygous (n = 15) dogs. Morphologic investigations including immunohistochemistry and lectin histochemistry were performed on selected homozygous animals (n = 15). RESULTS: Clinical fi...

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Publisher copy:
10.1167/iovs.04-0737

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Journal:
Investigative ophthalmology and visual science
Volume:
48
Issue:
9
Pages:
4240-4249
Publication date:
2007-09-01
DOI:
EISSN:
1552-5783
ISSN:
0146-0404
Source identifiers:
254194

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