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Apathy and disinhibition in frontotemporal dementia: Insights into their neural correlates.

Abstract:

BACKGROUND: Aberrant social behavior is a defining symptom of frontotemporal dementia (FTD) and may eventually occur in all syndromes composing the FTD spectrum. Two main behavioral abnormalities have been described: apathy and disinhibition, but their neuroanatomical correlates remain underspecified. METHODS: Sixty-two patients with a clinical diagnosis of FTD participated in the study. Voxel-based morphometry of MRI data was performed to explore the association between gray matter loss and...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Krueger, F More by this author
Nichelli, PF More by this author
Grafman, J More by this author
Journal:
Neurology
Volume:
71
Issue:
10
Pages:
736-742
Publication date:
2008-09-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:1452f3b5-bb72-45fd-a795-a3926e3de239
Source identifiers:
61344
Local pid:
pubs:61344

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