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Apathy and disinhibition in frontotemporal dementia: Insights into their neural correlates.

Abstract:

BACKGROUND: Aberrant social behavior is a defining symptom of frontotemporal dementia (FTD) and may eventually occur in all syndromes composing the FTD spectrum. Two main behavioral abnormalities have been described: apathy and disinhibition, but their neuroanatomical correlates remain underspecified. METHODS: Sixty-two patients with a clinical diagnosis of FTD participated in the study. Voxel-based morphometry of MRI data was performed to explore the association between gray matter loss and...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Neurology
Volume:
71
Issue:
10
Pages:
736-742
Publication date:
2008-09-01
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Source identifiers:
61344

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