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Journal article

Time-resolved fluorescence measurements using stroboscopic excitation

Abstract:

We report on the development of a simple technique for obtaining time-domain information using dc detection of fluorescence. We show that this is feasible for assays where a change in lifetime of an indicator occurs in reaction to an analyte, in fluorescence resonance energy transfer for example, and could be particularly useful for assays performed in the scaled-down environment of a "lab-on-a-chip", A rate equation model is presented which allows an objective analysis of the relative import...

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Journal:
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume:
5864
Pages:
1-7
Publication date:
2005-01-01
ISSN:
1605-7422
Language:
English
Pubs id:
pubs:132766
UUID:
uuid:14429a75-de10-4db9-9a05-d6d34d9796ac
Local pid:
pubs:132766
Source identifiers:
132766
Deposit date:
2012-12-19

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