Journal article
Insights into the U1 small nuclear ribonucleoprotein complex superfamily
- Abstract:
-
The 164 bp U1 small nuclear (sn) RNA is one of the most abundant noncoding (nc) RNA in human cells, estimated to be in the region of 106 copies/cell. Although best known for its role in pre-messenger RNA (mRNA) splicing events, research over the past 20 years has revealed diverse functions of this ncRNA in mammalian cell types. Excellent reviews exist detailing the role of U1 snRNA in pre-mRNA splicing events. This review highlights what is currently known regarding the additional roles, snRNP composition, expression profiles, and the genomic organization of this ncRNA.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 644.9KB, Terms of use)
-
- Publisher copy:
- 10.1002/wrna.1257
Authors
- Publisher:
- Wiley
- Journal:
- Wiley Interdisciplinary Reviews: RNA More from this journal
- Volume:
- 6
- Issue:
- 1
- Pages:
- 79-92
- Publication date:
- 2014-09-26
- Acceptance date:
- 2014-07-14
- DOI:
- EISSN:
-
1757-7012
- ISSN:
-
1757-7004
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:485863
- UUID:
-
uuid:1435e9b5-fd2c-404b-8f58-7349e42d6da5
- Local pid:
-
pubs:485863
- Source identifiers:
-
485863
- Deposit date:
-
2014-10-07
Terms of use
- Copyright holder:
- John Wiley & Sons, Ltd
- Copyright date:
- 2014
- Notes:
-
This is the author accepted manuscript following peer review version of the article. The final version is
available online from Wiley at: https://doi.org/10.1002/wrna.1257
If you are the owner of this record, you can report an update to it here: Report update to this record