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Secrets from immortal worms: What can we learn about biological ageing from the planarian model system?

Abstract:

Understanding how some animals are immortal and avoid the ageing process is important. We currently know very little about how they achieve this. While research in genetic model systems has revealed the existence of conserved genetic pathways and molecular processes that affect longevity. Most of these studies have been performed in established model organisms, amenable to both classical and molecular genetic approaches, with relatively short lifespans. Here we consider the use of planarians,...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.semcdb.2017.08.028

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Lady Margaret Hall
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Seminars in Cell and Developmental Biology Journal website
Volume:
70
Pages:
108-121
Publication date:
2017-08-15
Acceptance date:
2017-08-09
DOI:
EISSN:
1096-3634
ISSN:
1084-9521
Pmid:
28818620
Language:
English
Keywords:
Pubs id:
pubs:724200
UUID:
uuid:141ac384-2ac8-4507-898b-c3c59f03423e
Local pid:
pubs:724200
Source identifiers:
724200
Deposit date:
2017-08-26

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