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Journal article

Dissecting mammalian immunity through mutation.

Abstract:

Although mutation and natural selection have given rise to our immune system, a well-placed mutation can also cripple it, and within an expanding population we are recognizing more and more cases of single-gene mutations that compromise immunity. These mutations are an ideal tool for understanding human immunology, and there are more ways than ever to measure their physiological effects. There are also more ways to create mutations in the laboratory, and to use these resources to systematical...

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Publisher copy:
10.1038/icb.2014.8

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Immunology and cell biology
Volume:
92
Issue:
5
Pages:
392-399
Publication date:
2014-01-01
DOI:
EISSN:
1440-1711
ISSN:
0818-9641
URN:
uuid:140b031c-7312-4f88-9c88-b74bba548f3f
Source identifiers:
453198
Local pid:
pubs:453198

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