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Intrapleural agents for pleural infection: fibrinolytics and beyond.

Abstract:

PURPOSE OF REVIEW: Pleural infection is a common, increasing clinical problem with a high morbidity and mortality. Medical management of pleural infection often fails, requiring invasive thoracic surgery to drain infected pleural collections, and for many years intrapleural agents have been assessed to reduce the need for surgical drainage and improve clinical outcomes. Randomized trials assessing intrapleural fibrinolytic agents have given conflicting results, and recent evidence provides i...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Current opinion in pulmonary medicine
Volume:
18
Issue:
4
Pages:
326-332
Publication date:
2012-07-05
DOI:
EISSN:
1531-6971
ISSN:
1070-5287
URN:
uuid:13eafc03-cfc2-406b-9bde-ca3dc681a186
Source identifiers:
322692
Local pid:
pubs:322692

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