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Axonal Degeneration as a Predictor of Outcome in Neurological Disorders

Abstract:

This chapter reviews the role of axon degeneration as a predictor of clinical outcome in a spectrum of neurological disorders. This chapter begins with methods to asses damaged axons. This includes amyloid precursor protein Immunocytochemistry and cerebrospinal fluid "Surrogates." Axonal degeneration and loss, together with their surrogate markers, have emerged as important measures of the extent of damage to the central nervous system (CNS). This is reflected in studies of conditions as dive...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Elsevier
Pages:
373-387
Host title:
Multiple Sclerosis as A Neuronal Disease
Publication date:
2005-01-01
DOI:
Source identifiers:
381008
ISBN:
9780127387611
Pubs id:
pubs:381008
UUID:
uuid:13d12804-c78e-4ac3-a95c-97d3cb65ce2e
Local pid:
pubs:381008
Deposit date:
2013-11-16

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