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Modelling of Ca2+-activated chloride current in tracheal smooth muscle cells.

Abstract:

Stimulation of airway myocytes by contractile agents such as acetylcholine (ACh) activates a Ca2+-activated Cl- current (I(ClCa)) which may play a key role in calcium homeostasis of airway myocytes and hence in airway reactivity. The aim of the present study was to model I(ClCa) in airway smooth muscle cells using a computerised model previously designed for simulation of cardiac myocyte functioning. Modelling was based on a simple resistor-battery permeation model combined with multiple bind...

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Publication status:
Published

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Publisher copy:
10.1023/a:1014230611582

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Acta biotheoretica
Volume:
49
Issue:
4
Pages:
291-300
Publication date:
2001-01-01
DOI:
EISSN:
1572-8358
ISSN:
0001-5342
Source identifiers:
345925
Language:
English
Keywords:
Pubs id:
pubs:345925
UUID:
uuid:13c1ef28-237d-4686-94b2-36d7648d3368
Local pid:
pubs:345925
Deposit date:
2013-11-16

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