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Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (trigger): pragmatic, cluster randomised, feasibility trial.

Abstract:

OBJECTIVES and BACKGROUND: Transfusion thresholds for upper gastrointestinal bleeding (UGIB) are controversial. Observational studies suggest associations between liberal red blood cell (RBC) transfusion and adverse outcome. A recent trial reported increased mortality following liberal transfusion. We delivered a cluster randomised trial to evaluate the feasibility and safety of implementing a restrictive (transfusion when haemoglobin (Hb) <8 g dL) vs liberal (transfusion when Hb <10 g/...

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Journal:
Emergency medicine journal : EMJ
Volume:
31
Issue:
9
Pages:
780
Publication date:
2014-09-01
DOI:
EISSN:
1472-0213
ISSN:
1472-0205
Source identifiers:
481515
Language:
English
Keywords:
Pubs id:
pubs:481515
UUID:
uuid:13951e26-073c-4c9b-bd35-5f4963497c35
Local pid:
pubs:481515
Deposit date:
2014-08-29

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