Heat-inducible human factor that binds to a human hsp70 promoter.

Journal article

A factor found in nuclear extracts of human cells bound to the heat shock element of a human heat shock protein 70 gene. The level of this factor was significantly increased after heat shock. This induction was rapid and was not blocked by cycloheximide, suggesting that an initial event in the response of a human cell to heat is the activation of a preexisting regulatory factor.

Authors: Kingston, R; Schuetz, T; Larin, Z

• Publication status: Published
• Journal: Molecular and cellular biology
• Volume: 7
• Issue: 4
• Pages: 1530-1534
• Publication date: 1987-04-01
• EISSN: 1098-5549
• ISSN: 0270-7306
• Language: English
• Keywords: Hela Cells; Promoter Regions, Genetic; Molecular Weight; Hot Temperature; Genes; Humans; Heat-Shock Proteins; DNA-Binding Proteins; Base Sequence; Cell Nucleus