Journal article
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
- Abstract:
-
2-Oxoglutarate (2OG)-dependent oxygenases have important roles in the regulation of gene expression via demethylation of N-methylated chromatin components and in the hydroxylation of transcription factors and splicing factor proteins. Recently, 2OG-dependent oxygenases that catalyse hydroxylation of transfer RNA and ribosomal proteins have been shown to be important in translation relating to cellular growth, TH17-cell differentiation and translational accuracy. The finding that ribosomal oxy...
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Bibliographic Details
- Journal:
- Nature
- Volume:
- 510
- Issue:
- 7505
- Pages:
- 422-426
- Publication date:
- 2014-01-01
- EISSN:
-
1476-4687
- Source identifiers:
-
477946
Item Description
- Language:
- English
- Pubs id:
-
pubs:477946
- UUID:
-
uuid:13734a6f-2918-433d-9ee8-b267a2f20ec1
- Local pid:
- pubs:477946
- Deposit date:
- 2014-08-14
Terms of use
- Copyright date:
- 2014
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