Hypoxic depression of ventilation in humans: alternative models for the chemoreflexes.

Journal article

The ventilatory responses of 5 volunteers to three protocols were determined. In protocol A, PETCO2 was held at 1-2 Torr above resting; and PETO2 at 100 Torr for 10 min, 50 Torr for 20 min, and 100 Torr again for 10 min. In protocol B, PETCO2 was held at 8 Torr above resting, and PETO2 varied as in protocol A. Protocol C formed a control. Each protocol was repeated at least 6 times on each subject. The data were used to evaluate four different models (models 2-5) for incorporating the depress...

Expand abstract

Authors: Khamnei, S; Robbins, P

• Publication status: Published
• Journal: Respiration physiology
• Volume: 81
• Issue: 1
• Pages: 117-134
• Publication date: 1990-07-01
• DOI: 10.1016/0034-5687(90)90074-9
• ISSN: 0034-5687
• Language: English
• Keywords: Adult; Anoxia; Respiration; Carbon Dioxide; Oxygen Consumption; Female; Male; Models, Biological; Chemoreceptor Cells; Humans