Journal article
Increased expression of dysbindin-1A leads to a selective deficit in NMDA receptor signaling in the hippocampus
- Abstract:
-
The effects of the major schizophrenia susceptibility gene disease DTNBP1 on disease risk are likely to be mediated through changes in expression level of the gene product, dysbindin-1. How such changes might influence pathogenesis is, however, unclear. One possible mechanism is suggested by recent work establishing a link between altered dysbindin-1 expression and changes in surface levels of N-methyl-d-aspartate receptors (NMDAR), although neither the precise nature of this relationship, no...
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- Publisher copy:
- 10.1016/j.neuropharm.2011.08.007
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Bibliographic Details
- Journal:
- Neuropharmacology
- Volume:
- 61
- Issue:
- 8
- Pages:
- 1345-1353
- Publication date:
- 2011-12-01
- DOI:
- EISSN:
-
1873-7064
- ISSN:
-
0028-3908
- Source identifiers:
-
194650
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:194650
- UUID:
-
uuid:13649768-ed3a-43e8-a95e-910a6c4de5f6
- Local pid:
- pubs:194650
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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