Journal article icon

Journal article

Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: UK Heart and Renal Protection (UK HARP)-III. Rationale, trial design and baseline data

Abstract:

Background: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the natriuretic peptide system) may reduce these risks, but clinical...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1093/ndt/gfw321

Authors


More by this author
Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
More by this author
Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
Medical Research Council More from this funder
British Heart Foundation More from this funder
Cancer Research UK More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Nephrology, Dialysis and Transplantation Journal website
Volume:
32
Issue:
12
Pages:
2043-2051
Publication date:
2016-09-17
Acceptance date:
2016-07-14
DOI:
ISSN:
0931-0509 and 1460-2385
Pubs id:
pubs:641818
URN:
uri:135a35a4-74a5-42b2-a8b7-a250c9c59ff6
UUID:
uuid:135a35a4-74a5-42b2-a8b7-a250c9c59ff6
Local pid:
pubs:641818

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP