alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides

Journal article

Epimeric azidoesters containing a glucofuranosyl moiety are readily prepared from glucoheptonolactone and may be reduced to corresponding aminoesters; such compounds may be useful intermediates for the generation of combinatorial libraries of glucofuranose mimics and of spiroderivatives of glucofuranose at the anomeric position. The X-ray crystal structure of methyl 2-amino-2-deoxy-3,4-di-O-tert-butyldimethylsilyl-6,7-O-isopropylidene- β-D-gluco-heptulofuranosonate is reported.

Authors: Brandstetter, T; delaFuente, C; Kim, Y; Cooper, R; Watkin, D

• Publication status: Published
• Journal: TETRAHEDRON
• Volume: 52
• Issue: 32
• Pages: 10711-10720
• Publication date: 1996-08-05
• DOI: 10.1016/0040-4020(96)00594-7
• ISSN: 0040-4020
• Language: English