Journal article
Sputum microbiomic clustering in asthma and COPD reveals a Haemophilus‐predominant subgroup
- Abstract:
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Background:
Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti‐microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio. We hypothesized that sputum microbiomic clusters exist in stable airways disease, which can be differentiated by the sputum γP:F ratio.
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 1.0MB)
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- Publisher copy:
- 10.1111/all.14058
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Authors
Funding
Medical Research Council
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National Institute for Health Research
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Wellcome Trust
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AstraZeneca
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Allergy Journal website
- Volume:
- 75
- Issue:
- 4
- Pages:
- 808-817
- Publication date:
- 2019-09-25
- Acceptance date:
- 2019-08-27
- DOI:
- EISSN:
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1398-9995
- ISSN:
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0105-4538
- Pmid:
-
31556120
- Source identifiers:
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1063991
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:1063991
- UUID:
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uuid:13346dbf-2b01-4292-a010-7709061db921
- Local pid:
- pubs:1063991
- Deposit date:
- 2019-12-09
Terms of use
- Copyright holder:
- Diver et al.
- Copyright date:
- 2019
- Rights statement:
- © 2019 The Authors. Allergy Published by John Wiley and Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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