Journal article
ASYMMETRIC-SYNTHESIS OF (-)-(1R,2S)-CISPENTACIN AND RELATED CIS-2-AMINO AND TRANS-2-AMINO CYCLOPENTANE-1-CARBOXYLIC AND CYCLOHEXANE-1-CARBOXYLIC ACIDS
- Abstract:
- The antifungal antibiotic (-)-(1R,2S)-2-aminocyclopentane-1-carboxylic acid (cispentacin) 8 and its cyclohexane homologue 14 have been prepared utilizing the highly stereoselective conjugate addition of homochiral lithium N-benzyl-N-α-methylbenzylamide 5. The corresponding trans-β-amino acids 10 and 16 were also prepared via the selective epimerization of the cis-β-amino ester conjugate addition products.
- Publication status:
- Published
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Bibliographic Details
- Journal:
- JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
- Issue:
- 11
- Pages:
- 1411-1415
- Publication date:
- 1994-06-07
- DOI:
- EISSN:
-
1364-5463
- ISSN:
-
0300-922X
Item Description
- Pubs id:
-
pubs:110866
- UUID:
-
uuid:12f58856-2f2c-4ab1-9e18-2b5df9dc9e12
- Local pid:
- pubs:110866
- Source identifiers:
-
110866
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1994
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