Analysis of structural design features in collagen.

Journal article

The principles governing the molecular design of collagen have been investigated using molecular graphics to link the available sequence and X-ray diffraction data. The primary structure is classified into three regions of relevance to the intermolecular packing. Functionally important variations are revealed in the distribution of the amino acid residues. Solvent accessibility studies show that the formation of the triple helix is comparable to the stage of secondary structure formation in g...

Expand abstract

Authors: Jones, E; Miller, A

• Publication status: Published
• Journal: Journal of molecular biology
• Volume: 218
• Issue: 1
• Pages: 209-219
• Publication date: 1991-03-01
• DOI: 10.1016/0022-2836(91)90885-a
• EISSN: 1089-8638
• ISSN: 0022-2836
• Language: English
• Keywords: X-Ray Diffraction; Amino Acid Sequence; Computer Graphics; Protein Conformation; Macromolecular Substances; Collagen; Molecular Sequence Data; Models, Molecular