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Defining biochemical recurrence of prostate cancer after radical prostatectomy: a proposal for a standardized definition.

Abstract:

PURPOSE: Prostate-specific antigen (PSA) defined biochemical recurrence (BCR) of prostate cancer is widely used for reporting the outcome of radical prostatectomy (RP). A standardized BCR definition is lacking, and overall progression-free probability and risk of subsequent metastatic disease progression may vary greatly depending on the PSA criterion used. Ten definitions of BCR were evaluated to identify the one that best explains metastatic progression. METHODS: Of 3,125 patients who unde...

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Publisher copy:
10.1200/jco.2005.04.0756

Authors


Stephenson, AJ More by this author
Kattan, MW More by this author
Eastham, JA More by this author
Bianco, FJ More by this author
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Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume:
24
Issue:
24
Pages:
3973-3978
Publication date:
2006-08-05
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:12db34bd-82c3-4a9f-8f53-d0ba09bb1117
Source identifiers:
365958
Local pid:
pubs:365958

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