Journal article icon

Journal article

Localisation of AMPK γ subunits in cardiac and skeletal muscles.

Abstract:

The trimeric protein AMP-activated protein kinase (AMPK) is an important sensor of energetic status and cellular stress, and mutations in genes encoding two of the regulatory γ subunits cause inherited disorders of either cardiac or skeletal muscle. AMPKγ2 mutations cause hypertrophic cardiomyopathy with glycogen deposition and conduction abnormalities; mutations in AMPKγ3 result in increased skeletal muscle glycogen. In order to gain further insight into the roles of the different γ subunits...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s10974-013-9359-4

Authors


Grignani, RT More by this author
Watkins, H More by this author
Redwood, C More by this author
Journal:
Journal of muscle research and cell motility
Volume:
34
Issue:
5-6
Pages:
369-378
Publication date:
2013-12-05
DOI:
EISSN:
1573-2657
ISSN:
0142-4319
URN:
uuid:12d58bde-65d9-43e3-beaa-2125265f0487
Source identifiers:
429271
Local pid:
pubs:429271

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP