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Deletion at chromosome band 20p12.1 in colorectal cancer revealed by high resolution array comparative genomic hybridization.

Abstract:

Array comparative genomic hybridization (Array CGH) with tiling path resolution for a approximately 4.61 Mb region of chromosome band 20p12.1 has been used to investigate copy number loss in 48 colorectal cancer cell lines and 37 primary colorectal cancers. A recurrent deletion was detected in 55% of cell lines and 23% of primary cancers and the consensus minimum region of loss was identified as a approximately 190 kb section from 14.85 Mb to 15.04 Mb of chromosome 20. Two noncoding RNA genes...

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Publisher copy:
10.1002/gcc.20252

Authors


Davison, EJ More by this author
Tarpey, PS More by this author
Fiegler, H More by this author
Tomlinson, IP More by this author
Carter, NP More by this author
Journal:
Genes, chromosomes and cancer
Volume:
44
Issue:
4
Pages:
384-391
Publication date:
2005-12-05
DOI:
EISSN:
1098-2264
ISSN:
1045-2257
URN:
uuid:12c4075b-9152-4571-aa7a-91a3890c42f1
Source identifiers:
72244
Local pid:
pubs:72244

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