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Journal article

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.

Abstract:

Part of the substantial unexplained familial aggregation of breast cancer may be due to interactions between common variants, but few studies have had adequate statistical power to detect interactions of realistic magnitude. We aimed to assess all two-way interactions in breast cancer susceptibility between 70,917 single nucleotide polymorphisms (SNPs) selected primarily based on prior evidence of a marginal effect. Thirty-eight international studies contributed data for 46,450 breast cancer ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddt581

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Journal:
Human molecular genetics
Volume:
23
Issue:
7
Pages:
1934-1946
Publication date:
2014-04-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:12abda0c-8efa-4943-a018-0d33fa7982dd
Source identifiers:
464520
Local pid:
pubs:464520

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