- Abstract:
-
The ability to simultaneously monitor both the ionic current and fluorescence from membrane channels and pores has the potential to link structural changes with function in such proteins. We present a new method for simultaneously measuring single-channel electrical currents and fluorescence from membrane proteins by using water-in-oil droplet bilayers. We demonstrate the simultaneous fluorescence and electrical detection of stochastic blocking by cyclodextrin in multiple staphylococcal alpha...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1021/ja808128s
-
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- Journal:
- Journal of the American Chemical Society
- Volume:
- 131
- Issue:
- 5
- Pages:
- 1652-1653
- Publication date:
- 2009-02-05
- DOI:
- EISSN:
-
1520-5126
- ISSN:
-
0002-7863
- URN:
-
uuid:1285cfa3-7778-4955-b895-b141bc95c3c6
- Source identifiers:
-
34554
- Local pid:
- pubs:34554
- Copyright date:
- 2009
Journal article
Simultaneous measurement of ionic current and fluorescence from single protein pores.
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