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Journal article

Helping patients with persecutory delusions find safety

Abstract:

At the heart of a persecutory delusion is an incorrect perception of threat from others. This makes the person feel very unsafe. Overcoming such delusions therefore means establishing a sense of safety, and thus a realisation that there is no current threat. Discovering that one is safe functions as the counterweight to feeling unsafe. The counterweight shifts expectations and changes beliefs. In this article we describe how safety may be learned. This includes how to engage patients, framing the finding of safety, switching from threat to safety mode, using experiential learning, and consideration of blocking beliefs that may prevent new learning. Key points are to: frame intervention as an opportunity to find greater safety in the world so that meaningful activities can be resumed; repeatedly measure the learning of safety; make new benign associations with the internal and external cues driving the delusions; keep the new learning to the present and future, suitably circumscribed for an individual, so that potential for discord is limited; carry out safety-establishing behavioural experiments that allow for the dropping of defence behaviours, the reframing of evidence for the delusion, and diminish the pervasiveness of the perceived threat; and help patients move from situation-specific instances of safety to more generalised belief change. Enabling patients to re-discover safety in their everyday lives — decisively tipping the scales in favour of the counterweight — is the most transformational element of successful psychological intervention for persecutory delusions.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/schbul/sbag034

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Oxford college:
Magdalen College
Role:
Author
ORCID:
0000-0002-2541-2197


More from this funder
Funder identifier:
https://ror.org/0187kwz08
Grant:
NIHR305810


Publisher:
Oxford University Press
Journal:
Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders More from this journal
Volume:
52
Issue:
3
Article number:
sbag034
Publication date:
2026-06-04
Acceptance date:
2026-02-20
DOI:
EISSN:
1745-1701
ISSN:
0586-7614


Language:
English
Keywords:
Pubs id:
2379833
Local pid:
pubs:2379833
Deposit date:
2026-02-21
ARK identifier:

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