Journal article
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity
- Abstract:
-
While the induction of a neutralizing antibody response against HIV remains a daunting goal, data from both natural infection and vaccine-induced immune responses suggest that it may be possible to induce antibodies with enhanced Fc effector activity and improved antiviral control via vaccination. However, the specific features of naturally induced HIV-specific antibodies that allow for the potent recruitment of antiviral activity and the means by which these functions are regulated are poorl...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ National Institute of Allergy and Infectious Diseases
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Funding agency for:
Nigrovic, P
Grant:
R21-99435
+ National Institutes of Health
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Funding agency for:
Ercan, A
Grant:
K12 HD51959
R01 AI080289
+ Arthritis National Research Foundation
More from this funder
Funding agency for:
Ercan, A
Grant:
K12 HD51959
Bibliographic Details
- Publisher:
- American Society for Clinical Investigation Publisher's website
- Journal:
- Journal of clinical investigation Journal website
- Volume:
- 123
- Issue:
- 5
- Pages:
- 2183-2192
- Publication date:
- 2013-05-01
- Acceptance date:
- 2013-02-07
- DOI:
- EISSN:
-
1558-8238
- ISSN:
-
0021-9738
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:405990
- UUID:
-
uuid:128268b8-29d6-48e1-96ae-63677b859747
- Local pid:
- pubs:405990
- Source identifiers:
-
405990
- Deposit date:
- 2016-02-17
Terms of use
- Copyright holder:
- Journal of Clinical Investigation
- Copyright date:
- 2013
- Notes:
- Copyright © 2013, The American Society for Clinical Investigation.
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