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Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea A randomized controlled trial

Abstract:

Rationale: To establish a new approach to investigate the physiological effects of obstructive sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous positive airway pressure (CPAP) withdrawal. Objectives: To determine the effects of CPAP withdrawal. Methods: Forty-one patients with OSA and receiving CPAP were randomized to either CPAP withdrawal (subtherapeutic CPAP), or continued CPAP, for 2 weeks. Polysomnography, sleepiness, psychomotorperformance, endothelial ...

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Publisher copy:
10.1164/rccm.201106-0964OC

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Journal:
American Journal of Respiratory and Critical Care Medicine
Volume:
184
Issue:
10
Pages:
1192-1199
Publication date:
2011-11-15
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:127aabe9-c2f3-49b8-81ca-92223a539138
Source identifiers:
208585
Local pid:
pubs:208585

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