Journal article icon

Journal article

Association of NRAMP1 polymorphism with leprosy type but not susceptibility to leprosy per se in west Africans.

Abstract:

Twin and family studies indicate that host genetic factors influence susceptibility to leprosy and, possibly, leprosy type. Murine studies have suggested a role for the natural resistance-associated macrophage protein 1 (Nramp1) gene, which can influence cellular immune responses to intracellular pathogens. We evaluated a variation in the human homolog, NRAMP1, recently associated with tuberculosis susceptibility in West Africa. A total of 273 patients with leprosy and 201 controls from Mali ...

Expand abstract
Publication status:
Published

Actions


Authors


Meisner, SJ More by this author
Mucklow, S More by this author
Lienhardt, C More by this author
Expand authors...
Journal:
The American journal of tropical medicine and hygiene
Volume:
65
Issue:
6
Pages:
733-735
Publication date:
2001-12-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:1260c290-4ab3-4671-a036-a86184bf749f
Source identifiers:
32024
Local pid:
pubs:32024

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP