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An alpha-glucoside of 1,4-dideoxy-1,4-imino-D-lyxitol with an eleven carbon side chain

Abstract:

The distribution of pyrrolidine-type iminosugars with a long-side chain appears to be restricted to the relatively unrelated plant families Moraceae, Campanulaceae, and Hyacinthaceae. In a search for glycosidase inhibitors in these plant families, we isolated the 1,4-dideoxy-1,4-imino-d-lyxitol (DIL) glucoside bearing the 1,2,11-trihydroxyundec-4-ene side chain at the C-1α position from the roots of Adenophora triphylla. This iminosugar was a powerful and selective inhibitor of coffee bean α-...

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Publication status:
Published

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Journal:
PHYTOCHEMISTRY LETTERS
Volume:
3
Issue:
4
Pages:
230-233
Publication date:
2010-12-17
DOI:
ISSN:
1874-3900
URN:
uuid:125d5e6e-83ff-4849-9940-a51a10d9c2d3
Source identifiers:
124559
Local pid:
pubs:124559

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