Journal article icon

Journal article

The evolution of multiple drug resistance in malaria parasites.

Abstract:

Forces determining the rate of spread of drug resistance in malaria were explored using a genetics transmission model which took account of the strong population structure of these parasites. The rate of change of frequency of drug resistant mutants in the parasite population is primarily a function of the proportion of hosts treated with drugs, and parasite transmission rates. With high transmission rates, selection by drugs is more effective than with lower rates because the resistant mutan...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Hastings, IM More by this author
Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
92
Issue:
2
Pages:
188-195
Publication date:
1998
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:125344af-466a-451b-b49d-0a2cb88f8617
Source identifiers:
90603
Local pid:
pubs:90603

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP