Exploring and exploiting the therapeutic potential of glycoconjugates.

Journal article

Abstract:: Carbohydrates, either bound to proteins or in lipids, play essential roles as communication molecules in many intercellular and intracellular processes. In particular, carbohydrates are important mediators of cell-cell recognition events and have been implicated in related processes such as cell signaling regulation, cellular differentiation and immune response. This diverse utility has long suggested the power of carbohydrates in therapeutic approaches. This Concepts article highlights the recent potential uses of glycoconjugates as therapeutics, with particular reference to glycopeptides, glycoproteins, glycodendrimers, and glycoarrays.

Journal:: Chemistry (Weinheim an der Bergstrasse, Germany) More from this journal
Volume:: 12
Issue:: 3
Pages:: 656-665
Publication date:: 2006-01-01
DOI:: 10.1002/chem.200500557
EISSN:: 1521-3765
ISSN:: 0947-6539

Language:: English
Keywords:: Dendrimers

Drug Design

Glycoconjugates

Cell Differentiation

Humans

Animals

Signal Transduction
Pubs id:: pubs:33246
UUID:: uuid:1251b202-9274-43fb-b782-16dc92954af9
Local pid:: pubs:33246
Source identifiers:: 33246
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_1251b202927443fbb78216dc92954af9

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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