Journal article

CLEAVAGE OF THE 5-AMINO-5-CARBOXY-2-OXAPENTANOYL SIDE-CHAIN FROM ENZYMATICALLY SYNTHESIZED PENICILLINS AND CEPHALOSPORINS

Abstract:: Both 5R- and 5S-5-amino-5-carboxy-2-oxapentanoyl side chains can substitute for the L-δ-α-aminoadipoyl side chain in the isopenicillin N synthase catalysed formation of penicillins from tripeptides. The 5R- side chain analogue can be cleaved from penicillins and cephalosporins by treatment with D-amino acid oxidase followed by oxidative decarboxylation and decarboxylative elimination. © 1995.

Publication status:: Published

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APA Style

Baldwin, J., Davis, S., Forrest, A., & Schofield, C. (1995). CLEAVAGE OF THE 5-AMINO-5-CARBOXY-2-OXAPENTANOYL SIDE-CHAIN FROM ENZYMATICALLY SYNTHESIZED PENICILLINS AND CEPHALOSPORINS. BIOORGANIC and MEDICINAL CHEMISTRY LETTERS, 5(21), 2507–2512.

MLA Style

Baldwin, J, et al. “CLEAVAGE OF THE 5-AMINO-5-CARBOXY-2-OXAPENTANOYL SIDE-CHAIN FROM ENZYMATICALLY SYNTHESIZED PENICILLINS AND CEPHALOSPORINS.” BIOORGANIC and MEDICINAL CHEMISTRY LETTERS, vol. 5, no. 21, 1995, pp. 2507–12.

Chicago Style

Baldwin, J, S Davis, A Forrest, and C Schofield. 1995. “CLEAVAGE OF THE 5-AMINO-5-CARBOXY-2-OXAPENTANOYL SIDE-CHAIN FROM ENZYMATICALLY SYNTHESIZED PENICILLINS AND CEPHALOSPORINS.” BIOORGANIC and MEDICINAL CHEMISTRY LETTERS 5 (21): 2507–12.
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Publisher copy:: 10.1016/0960-894X(95)00436-W

Authors

+ Baldwin, J More by this author

Role:: Author

+ Davis, S More by this author

Role:: Author

+ Forrest, A More by this author

Role:: Author

+ Schofield, C More by this author

Role:: Author

Journal:: BIOORGANIC and MEDICINAL CHEMISTRY LETTERS More from this journal
Volume:: 5
Issue:: 21
Pages:: 2507-2512
Publication date:: 1995-11-02
DOI:: 10.1016/0960-894X(95)00436-W
ISSN:: 0960-894X

Language:: English
Pubs id:: pubs:44903
UUID:: uuid:122c8961-226b-4349-9edf-5fc0a8893075
Local pid:: pubs:44903
Source identifiers:: 44903
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_122c8961226b43499edf5fc0a8893075

Terms of use

Copyright date:: 1995

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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