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Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations.

Abstract:

Angiotensin 1-converting enzyme gene (ACE) is a risk factor for diabetic nephropathy (DN) in patients with type 1 diabetes. The selection of this candidate gene is supported by cross-sectional and follow-up studies, but no convincing family-based studies are available. Recruited were 1057 patients (with DN: persistent albuminuria with or without renal failure) and 1127 control subjects (long-standing [> or =15 yr] normoalbuminuric patients with type 1 diabetes) in Denmark, Finland, and Fra...

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Publication status:
Published

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Publisher copy:
10.1681/asn.2006101102

Authors


Hadjadj, S More by this author
Forsblom, C More by this author
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Journal:
Journal of the American Society of Nephrology : JASN
Volume:
18
Issue:
4
Pages:
1284-1291
Publication date:
2007-04-05
DOI:
EISSN:
1533-3450
ISSN:
1046-6673
URN:
uuid:1226af9e-8654-42c6-8fd4-256f5b41d8c3
Source identifiers:
19020
Local pid:
pubs:19020

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