Journal article
Humanization of an anti-mucin antibody for breast and ovarian cancer therapy.
- Abstract:
-
Antibody-drug conjugates utilize the targetting potential of antibodies to improve the potential of cytostatic or cytocidal drugs. One such murine monoclonal antibody, CTM01 (mCTM01), which recognizes an epitope on breast epithelial mucin, has potential for the treatment of breast and ovarian cancers. We examine in this paper the comparative properties of mCTM01 against a number of other anti-mucin antibodies. We then describe the humanization and high level re-expression of humanized CTM01 (...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Advances in experimental medicine and biology
- Volume:
- 353
- Pages:
- 61-82
- Publication date:
- 1994-01-01
- ISSN:
-
0065-2598
- Source identifiers:
-
171611
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:171611
- UUID:
-
uuid:121a7aea-9670-4a87-8e88-8bfc9eb1bbf6
- Local pid:
- pubs:171611
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1994
If you are the owner of this record, you can report an update to it here: Report update to this record