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AS03- and MF59-adjuvanted influenza vaccines in children

Abstract:

Influenza is a major cause of respiratory disease leading to hospitalization in young children. However, seasonal trivalent influenza vaccines (TIVs) have been shown to be ineffective and poorly immunogenic in this population. The development of live-attenuated influenza vaccines and adjuvanted vaccines are important advances in the prevention of influenza in young children. The oil-in-water emulsions MF59 and adjuvant systems 03 (AS03) have been used as adjuvants in both seasonal adjuvanted ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fimmu.2017.01760

Authors


Wilkins, AL More by this author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Pulendran, B More by this author
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Grant:
FP7 Grant “Advanced Immunization Technologies (ADITEC)”
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Grant:
Oxford Biomedical Research Centre
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
8
Issue:
DEC
Pages:
Article: 1760
Publication date:
2017-12-13
DOI:
ISSN:
1664-3224
Pubs id:
pubs:812267
URN:
uri:1209c489-c1ea-488e-9f26-529b55ea2244
UUID:
uuid:1209c489-c1ea-488e-9f26-529b55ea2244
Local pid:
pubs:812267

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