Journal article
Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol
- Abstract:
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Introduction The POInT study, an investigator initiated, randomised, placebo-controlled, double-blind, multicentre primary prevention trial is conducted to determine whether daily administration of oral insulin, from age 4.0 months to 7.0 months until age 36.0 months to children with elevated genetic risk for type 1 diabetes, reduces the incidence of beta-cell autoantibodies and diabetes.
Methods and analysis Infants aged 4.0 to 7.0 months from Germ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
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(Version of record, pdf, 620.4KB)
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- Publisher copy:
- 10.1136/bmjopen-2018-028578
Authors
Funding
+ Leona M. and Harry B. Helmsley Charitable Trust
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Grant:
2018PG-T1D022
2018PG-T1D062
Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- BMJ Open Journal website
- Volume:
- 9
- Issue:
- 6
- Article number:
- e028578
- Publication date:
- 2019-06-28
- Acceptance date:
- 2019-05-21
- DOI:
- EISSN:
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2044-6055
- Pmid:
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31256036
Item Description
- Language:
- English
- Pubs id:
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pubs:1028278
- UUID:
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uuid:11fd0a0c-4bb0-4a3a-84b0-0543785eef46
- Local pid:
- pubs:1028278
- Source identifiers:
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1028278
- Deposit date:
- 2019-07-26
Terms of use
- Copyright holder:
- Ziegler, A-G wt al
- Copyright date:
- 2019
- Notes:
- © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
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