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Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH

Abstract:
The two-electron electrochemical oxidation of dopamine is studied voltammetrically at gold macroelectrodes around neutral pH with simulations used to give kinetic and mechanistic data. In particular, the system shows "potential inversion" in which the thermodynamic oxidation potential of dopamine to form the corresponding semi-quinone formation occurs at a more positive potential than that of the oxidation of the semi-quinone to the quinone form. The use of Tafel slopes measured from the voltammograms as a function of the voltage scan rate is show to be a particularly sensitive indicator of mechanism showing the effect of the follow-up chemistry in which the two-electron oxidation product undergoes an irreversible cyclization reaction.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c9cp05527d

Authors

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Role:
Author
ORCID:
0000-0001-8742-2158
More by this author
Role:
Author
ORCID:
0000-0002-2428-0751
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
St John's College
Role:
Author
ORCID:
0000-0001-9841-5041


Publisher:
Royal Society of Chemistry
Journal:
Physical Chemistry Chemical Physics More from this journal
Volume:
22
Issue:
2
Pages:
607-614
Publication date:
2019-11-20
Acceptance date:
2019-11-20
DOI:
EISSN:
1463-9084
ISSN:
1463-9076
Pmid:
31776536


Language:
English
Keywords:
Pubs id:
pubs:1075764
UUID:
uuid:11d17b1c-c56e-49bf-9927-47f4d720e35f
Local pid:
pubs:1075764
Source identifiers:
1075764
Deposit date:
2019-12-02
ARK identifier:

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