Successful placentation in the human is dependent on the trophoblast evading recognition and destruction by the maternal immune system. However, invasive cytotrophoblast express HLA-G which may be able to present peptide to T cells. Transporter proteins are essential for peptide presentation and major histocompatibility complex (MHC) class I assembly. We have determined their expression by trophoblast in relation to HLA-G, using immunohistochemistry. Anti-transporter protein antibody (TAP1) l...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Expression of TAP1 by human trophoblast.
If you are the owner of this record, you can report an update to it here: Report update to this record