- Abstract:
-
Antibiotic-resistant bacteria, particularly Gram negative species, present significant health care challenges. The permeation of antibiotics through the outer membrane is largely effected by the porin superfamily, changes in which contribute to antibiotic resistance. A series of antibiotic resistant E. coli isolates were obtained from a patient during serial treatment with various antibiotics. The sequence of OmpC changed at three positions during treatment giving rise to a total of four OmpC...
Expand abstract - Publisher copy:
- 10.1371/journal.pone.0025825
-
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- Journal:
- PLoS ONE
- Volume:
- 6
- Issue:
- 10
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1932-6203
- URN:
-
uuid:11b7908d-63ca-4f4b-a66b-72ad33a2a048
- Source identifiers:
-
306231
- Local pid:
- pubs:306231
- Language:
- English
- Copyright date:
- 2011
Journal article
Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli
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