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Inhaled nitric oxide in preterm infants: an individual-patient data meta-analysis of randomized trials.

Abstract:

BACKGROUND: Inhaled nitric oxide (iNO) is an effective therapy for pulmonary hypertension and hypoxic respiratory failure in term infants. Fourteen randomized controlled trials (n = 3430 infants) have been conducted on preterm infants at risk for chronic lung disease (CLD). The study results seem contradictory. DESIGN/METHODS: Individual-patient data meta-analysis included randomized controlled trials of preterm infants (<37 weeks' gestation). Outcomes were adjusted for trial differences ...

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Publisher copy:
10.1542/peds.2010-2725

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Journal:
Pediatrics
Volume:
128
Issue:
4
Pages:
729-739
Publication date:
2011-10-05
DOI:
EISSN:
1098-4275
ISSN:
0031-4005
URN:
uuid:11ac092b-11de-4e73-8eb1-676f8f06e86c
Source identifiers:
435029
Local pid:
pubs:435029

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