- Abstract:
-
Susceptibility to the rectal pathogen Microbacterium nematophilum provides a means of examining hindgut differentiation in C. elegans. Mutants of bus-1 are resistant to infection with this pathogen. We show here that bus-1 encodes a predicted acyltransferase expressed in rectal epithelial cells (K, F, and U), suggesting its involvement in regional surface modification. bus-1 reporter genes were used to show spatial regulation by hindgut developmental control genes: egl-38, mab-9, and mab-23. ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/dvdy.21792
-
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- Journal:
- Developmental dynamics : an official publication of the American Association of Anatomists
- Volume:
- 237
- Issue:
- 12
- Pages:
- 3762-3776
- Publication date:
- 2008-12-05
- DOI:
- EISSN:
-
1097-0177
- ISSN:
-
1058-8388
- URN:
-
uuid:116b50a1-3e4f-474d-ad14-21c7a2fa4daf
- Source identifiers:
-
202876
- Local pid:
- pubs:202876
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
The acyltransferase gene bus-1 exhibits conserved and specific expression in nematode rectal cells and reveals pathogen-induced cell swelling.
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