Journal article

Partial reduction of electron-deficient pyridines

Abstract:: The partial reduction of electron-deficient pyridines is described herein. Mono- and disubstituted pyridines can be transformed into functionalized dihydropyridines using either Birch reduction conditions or sodium/naphthalene in THF. The compounds formed by these high-yielding reductive alkylation protocols have potential as synthetic intermediates, and we have shown that bicyclo compounds containing 6,5, 6,6, and 6,7 ring systems can be prepared in one step via a base-promoted cylization.

Publication status:: Published

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APA Style

Donohoe, T., McRiner, A., & Sheldrake, P. (2000). Partial reduction of electron-deficient pyridines. Organic Letters, 2(24), 3861–3863.

MLA Style

Donohoe, T, et al. “Partial Reduction of Electron-Deficient Pyridines.” Organic Letters, vol. 2, no. 24, 2000, pp. 3861–63.

Chicago Style

Donohoe, T, A McRiner, and P Sheldrake. 2000. “Partial Reduction of Electron-Deficient Pyridines.” Organic Letters 2 (24): 3861–63.
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Publisher copy:: 10.1021/ol0065930

Authors

+ Donohoe, T More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ McRiner, A More by this author

Role:: Author

+ Sheldrake, P More by this author

Role:: Author

Journal:: Organic letters More from this journal
Volume:: 2
Issue:: 24
Pages:: 3861-3863
Publication date:: 2000-11-01
DOI:: 10.1021/ol0065930
EISSN:: 1523-7052
ISSN:: 1523-7060

Language:: English
Pubs id:: pubs:31787
UUID:: uuid:11372ce7-44b8-4bc2-8781-4d20a5aebc95
Local pid:: pubs:31787
Source identifiers:: 31787
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_11372ce744b84bc287814d20a5aebc95

Terms of use

Copyright date:: 2000

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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