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An Analysis of Deformation Dependent Electromechanical Coupling in the Mouse Heart

Abstract:
To investigate the effects of the coupling between excitation and contraction on whole-organ function, we have developed a novel biophysically based multiscale electromechanical model of the murine heart. Through comparison with a comprehensive in vivo experimental data set, we show good agreement with pressure and volume measurements at both physiological temperatures and pacing frequencies. ...

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Publisher copy:
10.1113/jphysiol.2012.231928

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Journal:
Journal of Physiology More from this journal
Publication date:
2012-05-01
DOI:
ISSN:
0022-3751, 1469-7793


UUID:
uuid:11345612-2e37-42f1-98d4-85a4bb268f73
Local pid:
cs:6072
Deposit date:
2015-03-31

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