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Sonosensitive Nanoparticles for Controlled Instigation of Cavitation and Drug Delivery by Ultrasound

Abstract:

Reliable instigation of cavitation in-vivo during ultrasound therapy is notoriously difficult. Lowering the peak rarefractional pressure required to initiate cavitation (the cavitation threshold) has been previously addressed using ultrasound contrast agents in the form of encapsulated stabilized micron scale bubbles. These agents lack stability and are generally too large to extravasate into tumours and other target tissues. Solid nanoparticles are proposed as novel cavitation nucleation age...

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Publication status:
Published

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Publisher copy:
10.1063/1.4757372

Authors


Wagstaffe, SJ More by this author
Schiffter, HA More by this author
Coussios, C-C More by this author
Volume:
1481
Pages:
426-431
Publication date:
2012
DOI:
EISSN:
1551-7616
ISSN:
0094-243X
URN:
uuid:1122752c-0c67-4872-9819-75857aff1eaa
Source identifiers:
384425
Local pid:
pubs:384425
ISBN:
9780735410930

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