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Enhanced choline and Rb+ transport in human erythrocytes infected with the malaria parasite Plasmodium falciparum.

Abstract:

Human erythrocytes infected in vitro with the malaria parasite Plasmodium falciparum showed a markedly increased rate of choline influx compared with normal cells. Choline transport into uninfected cells (cultured in parallel with infected cells) obeyed Michaelis-Menten kinetics (Km approximately 11 microM). In malaria-parasite-infected cells there was an additional choline-transport component which failed to saturate at extracellular concentrations of up to 500 microM. This component was les...

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Publication status:
Published

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Authors


Elford, BC More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Ellory, JC More by this author
Journal:
The Biochemical journal
Volume:
278 ( Pt 2)
Issue:
2
Pages:
521-525
Publication date:
1991-09-05
EISSN:
1470-8728
ISSN:
0264-6021
URN:
uuid:111f9f7c-1ff3-4e74-b8c6-de423e99e87b
Source identifiers:
24718
Local pid:
pubs:24718

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