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Platelet-induced autoagglutination of Plasmodium falciparum-infected red blood cells and disease severity in Thailand.

Abstract:

The relationship of the platelet-mediated autoagglutination of Plasmodium falciparum-infected red blood cells (IRBCs) to disease severity was investigated in 182 Thai patients with falciparum malaria; it was evident in 43% of uncomplicated malaria (n=63), 41% of severe malaria (n=104), and 100% of cerebral malaria (n=15; P=.001) isolates. The median (range) number of IRBCs in agglutinates per 1000 IRBCs was significantly higher in cerebral malaria (6 [3-42]) than in severe (0 [0-52]) and unco...

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Publication status:
Published

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Publisher copy:
10.1086/381900

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Journal:
The Journal of infectious diseases
Volume:
189
Issue:
6
Pages:
1052-1055
Publication date:
2004-03-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:111d5821-3837-49b7-907c-bca275db3d37
Source identifiers:
38996
Local pid:
pubs:38996

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