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Journal article

Selection of drug resistance-mediating Plasmodium falciparum genetic polymorphisms by seasonal malaria chemoprevention in Burkina Faso.

Abstract:

Seasonal malaria chemoprevention (SMC), with regular use of amodiaquine plus sulfadoxine-pyrimethamine (AQ/SP) during the transmission season, is now a standard malaria control measure in the Sahel subregion of Africa. Another strategy under study is SMC with dihydroartemisinin plus piperaquine (DP). Plasmodium falciparum single nucleotide polymorphisms (SNPs) in P. falciparum crt (pfcrt), pfmdr1, pfdhfr, and pfdhps are associated with decreased response to aminoquinoline and antifolate antim...

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Publication status:
Published

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Publisher copy:
10.1128/aac.02406-14

Authors


Compaoré, YD More by this author
Sakandé, S More by this author
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Publisher:
American Society for Microbiology
Journal:
Antimicrobial agents and chemotherapy
Volume:
58
Issue:
7
Pages:
3660-3665
Publication date:
2014-07-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:111aa5ee-2d86-447b-a3af-58f1208fa5ad
Source identifiers:
462230
Local pid:
pubs:462230
Language:
English

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