Journal article

Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.

Abstract:: Carboxymethylproline synthase was shown to condense L-glutamate semialdehyde with malonyl-coenzyme A to produce (2S,5S)-carboxymethylproline, while incubation of D-glutamate semialdehyde results only in uncoupled turnover of malonyl-CoA.

Publication status:: Published

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APA Style

Sorensen, J., Sleeman, M., & Schofield, C. (2005). Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis. Chemical Communications, 9, 1155–1157.

MLA Style

Sorensen, J, et al. “Synthesis of Deuterium Labelled L- and D-Glutamate Semialdehydes and Their Evaluation as Substrates for Carboxymethylproline Synthase (CarB)--Implications for Carbapenem Biosynthesis.” Chemical Communications, no. 9, 2005, pp. 1155–57.

Chicago Style

Sorensen, J, M Sleeman, and C Schofield. 2005. “Synthesis of Deuterium Labelled L- and D-Glutamate Semialdehydes and Their Evaluation as Substrates for Carboxymethylproline Synthase (CarB)--Implications for Carbapenem Biosynthesis.” Chemical Communications, no. 9: 1155–57.
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Publisher copy:: 10.1039/b416423g

Authors

+ Sorensen, J More by this author

Role:: Author

+ Sleeman, M More by this author

Role:: Author

+ Schofield, C More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Chemical Communications More from this journal
Issue:: 9
Pages:: 1155-1157
Publication date:: 2005-03-01
DOI:: 10.1039/b416423g
EISSN:: 1364-548X
ISSN:: 1359-7345

Language:: English
Keywords:: Carbapenems

Stereoisomerism

Glutamic Acid

Deuterium

Aldehydes

Isotope Labeling

Molecular Structure

Carbon-Carbon Lyases
Pubs id:: pubs:33010
UUID:: uuid:1119e63e-35b7-493f-b9b9-e4e4a84f89f1
Local pid:: pubs:33010
Source identifiers:: 33010
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_1119e63e35b7493fb9b9e4e4a84f89f1

Terms of use

Copyright date:: 2005

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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