Olsalazine in patients intolerant of sulphasalazine.

Journal article

Fifty patients with ulcerative colitis, intolerant of sulphasalazine, were treated with 500 mg olsalazine twice daily for a 3-month trial period. Thirty-eight of the patients (76%) tolerated the drug well, and all continued to take it beyond the 3-month period. Twelve (24%) were withdrawn because of side effects, the commonest being diarrhoea. There were no haematologic or biochemical abnormalities. Thus, olsalazine is a useful drug for patients who are intolerant of sulphasalazine.

Authors: Ireland, A; Jewell, D

• Publication status: Published
• Publisher: Informa Healthcare
• Journal: Scandinavian journal of gastroenterology
• Volume: 22
• Issue: 9
• Pages: 1038-1040
• Publication date: 1987-11-01
• DOI: 10.3109/00365528708991953
• EISSN: 1502-7708
• ISSN: 0036-5521
• Language: English
• Keywords: Aged; Male; Aminosalicylic Acids; Female; Sulfasalazine; Clinical Trials as Topic; Colitis, Ulcerative; Adult; Humans; Middle Aged